Non-specific cell-mediated immunity in Nigerian children with uncomplicated malaria
نویسندگان
چکیده
منابع مشابه
Efficacy of artemisinin combination therapy for the treatment of uncomplicated falciparum malaria in Nigerian children.
INTRODUCTION The development and spread of Plasmodium falciparum resistance to most commonly used antimalarials remain a major challenge in the control of malaria. Constant monitoring of drug efficacy is an important tool in establishing rational antimalarial drug policies. METHODOLOGY A randomized comparative study was conducted at the Wesley Guild Hospital, Ilesa, Nigeria between February 2...
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Yamakido, et al. in 1986 have studied immunological parameters in poison gas workers, and a depression has been observed in immunologic response. Also, the frequency of cancer has reached as high as five-fold that of the general population. In the present study, cell-mediated immunity (CMI) was measured in three groups of Iranian mustard gas-injured patients. The first group were those wh...
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Staphylokinase is a highly fibrin-specific clot-dissolving agent that constitutes a promising drug for clinical development. It is of bacterial origin, and the majority of patients develop neutralizing Ab after its administration. Several antigenic regions, recognized by these Ab, have been identified, but the underlying immunogenic features of staphylokinase remain unknown. In this study, we s...
متن کاملLymphocyte Perturbations in Malawian Children with Severe and Uncomplicated Malaria
Lymphocytes are implicated in immunity and pathogenesis of severe malaria. Since lymphocyte subsets vary with age, assessment of their contribution to different etiologies can be difficult. We immunophenotyped peripheral blood from Malawian children presenting with cerebral malaria, severe malarial anemia, and uncomplicated malaria (n = 113) and healthy aparasitemic children (n = 42) in Blantyr...
متن کاملReversible Audiometric Threshold Changes in Children with Uncomplicated Malaria
Background. Plasmodium falciparum malaria, as well as certain antimalarial drugs, is associated with hearing impairment in adults. There is little information, however, on the extent, if any, of this effect in children, and the evidence linking artemisinin combination therapies (ACTs) with hearing is inconclusive. Methods. Audiometry was conducted in children with uncomplicated malaria treated ...
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ژورنال
عنوان ژورنال: Biokemistri
سال: 2005
ISSN: 0795-8080
DOI: 10.4314/biokem.v17i1.32589